WebWe'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2024 ... Cytohesin-2 (CYTH2), formerly known as Pleckstrin homology, Sec7 and coiled/coil domains 2 (PSCD2), is a member of the cytohesin family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH dom…
CYTH2 protein expression summary - The Human Protein …
Web(Click on the icon in the table below to see search hit context) Web产品详细信息. MA1-062 detects recombinant human and mouse cytohesin-1 and 2 (ARNO). MA1-062 has been successfully used in Western blot, IF and immunoprecipitation procedures. By Western blot, this antibody detects an ~48 kDa band representing both cytohesin-1 and cytohesin-2. In immunoprecipitation procedures MA1-062 only … in wall lights
sort1 related genes - GeneCards Search Results
WebNX_Q99418 - CYTH2 - Cytohesin-2 - Localization. Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Activates ARF factors through replacement of GDP with GTP (By similarity). The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane … WebJul 16, 2004 · The pleckstrin homology (PH) domains of the homologous proteins Grp1 (general receptor for phosphoinositides), ARNO (Arf nucleotide binding site opener), and Cytohesin-1 bind phosphatidylinositol (PtdIns) 3,4,5-trisphosphate with unusually high selectivity ... Macromolecules Find similar proteins by: (by identity cutoff) 3D Structure WebENCODES a protein that exhibits inositol 1,4,5 trisphosphate binding (ortholog); INVOLVED IN negative regulation of dendrite development (ortholog); PARTICIPATES IN Arf family mediated signaling pathway; phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH developmental and epileptic encephalopathy 12 (ortholog); FOUND … in wall linear drain