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WebABO incompatibility produces severe immune-mediated hemolytic reactions. The anti-A and/or anti-B IgM alloantibodies in the recipient's plasma produce intravascular hemolysis (circulating RBC fragments, hemoglobinemia, and hemoglobinuria) of the donor's RBCs. WebABO incompatibility can cause acute hemolytic transfusion reactions (AHTR), hemolytic disease of the fetus and …. Management of non-RhD red blood cell alloantibodies during pregnancy. …exposed to a non-O fetus . In contrast to other IgG alloantibodies, severe hemolysis due to ABO incompatibility is usually a problem for the neonate and ... the pod bods
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